Polysubstance use refers to the consumption of two or more substances simultaneously or within a short time frame.   This practice can occur either intentionally, where individuals seek to enhance or modify the effects of the substances, or unintentionally, such as when drugs are mixed without the user's knowledge, often leading to dangerous outcomes.   Polysubstance use has gained attention due to its association with increased risks of overdose and other health complications.   .Keep ReadingCartels, graft at Health ministry will test nerve of Dr BarasaNo new mpox cases confirmed since July 22, Health ministry saysKenya confirms one Mpox case, steps up surveillance at borderAfrica's CDC declares mpox a public health emergencyThe term lacks a consistent definition across various fields, but it generally encompasses the use of multiple substances, which may include illicit drugs, prescription medications, and alcohol.   Intentional use occurs when individuals deliberately combine substances to achieve specific effects, such as intensifying a high or counteracting negative side effects.   Unintentional use often happens when users consume substances that are unknowingly mixed with others.   The combination of different substances can lead to unpredictable effects, increasing the risk of overdose and severe health issues.  In 2022, nearly half of all drug overdose deaths involved multiple substances.   Polysubstance dependence is characterized by the indiscriminate use of at least three different classes of substances without a primary substance preference.   This condition can complicate treatment and recovery due to the varied effects and withdrawal symptoms associated with different drugs.   Polysubstance use presents significant challenges for public health due to its complexity and the heightened risks involved.   Understanding the motivations behind this behavior-whether for recreational purposes or as a means of self-medication-is crucial for developing effective prevention and treatment strategies. [Mugambi Mbaabu, psychologist/psychiatrist clinical officer and lecturer KMTC Meru Campus] Health Mental Health Living Previous article Why walking barefoot is a game changer for your health Next article Cervical Cancer Awareness Month: Key facts you should know