The changes are aimed at enhancing service delivery in the various ministries.
The motorists termed Ndung'u and Kandie's resignations as 'deeply concerning' and 'sudden'.
Nyachae had previously been shortlisted to become the new chair of the IEBC.
Karua has been in politics for close to three decades.
Her sentiments come in the wake of the heightened youth killings.
The latest incident follows similar reports at Alliance Girls High School.
Motorists were advised to plan accordingly.
The disruption comes days after KRA recorded a growth in its revenue collection.
This came after KeRRA and KeNHA bosses stepped down in quick succession.
Kenya experiences an influx of fake goods into its market on a regular basis.